HUMAN

MDHC_HUMAN_v1  hMDH1 Cytosolic Human Malate Dehydrogenase 1 transcript variant 1. (DataSheet / SnapGeneFile)

MDHC_HUMAN_v2  hMDH1 Cytosolic Human Malate Dehydrogenase 1 transcript variant 2. (DataSheet / SnapGeneFile)

MDHC_HUMAN_v3  hMDH1 Cytosolic Human Malate Dehydrogenase 1 transcript variant 3. (DataSheet / SnapGeneFile)

 MDHM_HUMAN hMDH2 Mitochondrial Human Malate Dehydrogenase 2 transcript variant 1. (DataSheet / SnapGeneFile)

YEAST

MDHM_YEAST Yeast Mitochondrial MDH1  Expression highly changes based on metabolite starting point and its involvement in the Asp-malate shuttle in yeast extends replicative lifespan and may play a role in calorie-restricted life extension. (DataSheet / SnapGeneFile)

 MDHC_YEAST Yeast Cytoplasmic  MDH2 Interacts with PEPCK and Fructose Bisphosphatase1  This isoform is reported to translocate to nuclear periphery in response to DNA damage.  (DataSheet / SnapGeneFile)

 MDHP_YEAST Yeast Peroxisomal  MDH3  The affinity of MDH3 for OAA is lower than those of MDH1 and MDH2. The structure of the ternary complex suggests that the active-site loop is in the open conformation, differing from the closed conformations in mitochondrial and cytosolic malate dehydrogenases. (DataSheet / SnapGeneFile)